Tag Archives: agn

After Hours: Allergan, Tesla Motors, Walt Disney Shares Fall

Allergan ( AGN ) tumbled on new tax inversion rules, Tesla Motors ( TSLA ) skidded on weak Q1 deliveries and Walt Disney ( DIS ) retreated as a key executive exited, raising doubts about who might be the eventual successor to CEO Bob Iger. Allergan stock fell 21% after the Treasury Department issued new rules to curb so-called tax inversions. That includes steps to curb earnings stripping, a method used to reduce taxes after an inversion. Pfizer ( PFE ) and Ireland-based plan to merge, with Pfizer’s takeover structured to reduce U.S. tax liability. Pfizer stock edged higher late after closing up 2.3%. Allergan had closed 3.5% higher. Tesla Motors said that it delivered 14,820 vehicles in Q1, up nearly 50% vs. a year earlier but below the company’s February forecast for 16,000. Tesla blamed “severe” parts shortages for the Model X crossover — and its own “hubris.” Tesla shares fell 4% late, erasing nearly all its 4% regular-session gain on huge preorders for the Model 3.  The Model 3 is supposed to go into production by late 2017, with total vehicle production hitting 500,000 by 2020. Walt Disney said after the close that COO Thomas Staggs, who was seen as a possible successor to CEO Bob Iger, is leaving May 6. Staggs will serve as a special advisor to Iger. Disney stock fell 2% after closing down 0.4%. Meanwhile, Salesforce.com ( CRM ) agreed to buy artificial intelligence startup MetaMind for undisclosed terms, the latest big tech to step up AI takeovers and investments. Salesforce CEO Marc Benioff invested in MetMind back in December 2014. Salesforce stock was little changed late.

Allergan Price Target Cut On Merger Delay, Weak Q1 Forecast

Drugmaker Allergan ( AGN ) got a price-target cut from Canaccord Genuity Thursday after the company hit a delay in its merger with Pfizer ( PFE ), among other issues. Analyst Corey Davis noted that on Wednesday, the Federal Trade Commission (FTC) had asked for additional information on the Pfizer-Allergan merger , which was first announced in November. The companies also have to wait until Allergan finishes divesting its generic-drug business to Teva Pharmaceutical Industries ( TEVA ), which itself hit a delay this month that caused Teva to push the expected closing date from Q1 to June. Pfizer and Allergan still expect to close their $160 billion merger in the second half of this year. “In the meanwhile, we are lowering our Q1 estimates (EPS drops from $3.43 to $2.89) as it’s always the weakest quarter for specialty pharma, and we feel the rest of the Street is also too high,” Davis wrote in his research note lowering his price target on Allergan stock to 320 from 340. “This has been a trend in the past several years and is partly because of the reset of Medicare Part D.” Davis added that the merger of Target ( TGT ) and CVS Health ( CVS ) should hit Allergan’s distribution business to the tune of $500 million a year, and the launch of bowel-disease drug Viberzi has increased spending. Davis wrote that he is nonetheless maintaining his buy rating due to the high likelihood that the deal will close. There has been some skepticism among investors over whether the Pfizer-Allergan deal is going to close this year — besides the signals from Allergan’s falling stock price, a buy-side survey by Evercore ISI analyst Mark Schoenebaum this month found that a fifth of respondents place the odds at less than 50%. Along with the FTC’s backlog, there’s concern that the incoming president and Congress might do something to limit tax-inversion deals like this one, as some candidates have threatened to do. Pfizer’s leadership and Wall Street analysts have been more confident, however. On March 8, Deutsche Bank analyst Gregg Gilbert wrote that the gap between Pfizer’s offer price and Allergan’s stock price — then $47 — presents a buying opportunity as it will likely narrow as the deal closing nears. Allergan stock was down a fraction in morning trading on the stock market today , near 274.

Alder BioPharma Migraine Drug Scores In Trial; Stock Spikes

Small biotech Alder BioPharmaceuticals ( ALDR ) soared more than 50% to a two-month high in early trading Monday after its migraine drug candidate succeeded in a mid-stage trial, positioning it to compete with some giant rivals. Alder said that a single intravenous infusion of its monoclonal antibody, ALD403, had significantly reduced migraine days over a 12-week period compared to a placebo. Depending on the dose, between 44% and 57% of patients experienced a 50% reduction in migraine days, while 27% to 33% experienced a 75% reduction. “Evaluation of ALD403 continues to exhibit a potential best-in-class profile, which includes immediate, significant and durable migraine prevention with infrequent quarterly dosing,” Alder CEO Randall Schatzman said in a statement. “With our commitment to the accelerated development of ALD403 reinforced by today’s positive results, we look forward to advancing our development plan, and assuming FDA approval, independently marketing ALD403 in the U.S. to meet the critical medical needs of the 13 million patients nationwide who are candidates for migraine prevention therapy.” Alder’s decision to market its drug without a big-pharma partner, unusual for a small biotech, could pit it against some very big competitors developing similar drugs. ALD403 is an anti-calcitonin gene-related peptide (CGRP) antibody, similar to migraine candidates being developed by Amgen ( AMGN ), Teva Pharmaceutical Industries ( TEVA ) and Eli Lilly ( LLY ). Alder’s drug is distinguished by its infrequent dosing: Amgen and Teva’s drugs are injected once a month, while Lilly’s is biweekly. It would also be competing against Allergan ‘s ( AGN ) Botox, which is also quarterly but involves 31 separate shots. Credit Suisse analyst Vamil Divan wrote that ALD403’s results seem roughly equivalent to Teva’s in terms of effectiveness, but he did note that there was no significant improvement over the placebo in the number of patients who experienced a 100% reduction in migraine days. Between 4% and 8% of patients on the drug achieved this, which was rather lower than the 16% who had been headache-free in a previous trial. Alder stock, like so many other biotech stocks, had lost more than half its value since touching its all-time peak of 54.90 in July. But in early trading on the stock market today , shares were was up some 52% near 26. Image provided by Shutterstock .